Dean of dental school up to five retractions for cancer research papers – Retraction Watch

Russell Taichman

A dental school dean who has published cancer research papers is up to five withdrawals.

Russell Taichmanthe dean of the University of Alabama at Birmingham School of Dentistry, lost two papers in Research against cancer earlier this month, after losing three more since 2020. Most of the retractions came after PubPeer comments about duplicate images in some articles.

In April 2020, Elisabeth Bik commented on two of the by Taichman papers which would later be retracted, highlighting potentially recycled images between articles.

None of the authors responded on PubPeer, but Taichman apparently took her comments to heart and credited her in a retraction notice.

The withdrawal to remark for “Various signaling pathways via the SDF-1/CXCR4 chemokine axis in prostate cancer cell lines lead to altered cytokine secretion and angiogenesis patterns“, originally published in 2005 in Cell signalingstated that the corresponding author, Taichman, requested the action:

This article has been removed at the request of the authors. The corresponding author wishes to withdraw the above article because Dr. Elisabeth Bik pointed out that some of the figures, including Figure 1B and Figure 6A, were duplicated. The corresponding author wishes to convey his sincere regrets to the editor and readers of the journal Cellular Signaling.

Taichman, who was at the University of Michigan School of Dentistry in Ann Arbor when the five retracted articles were originally published, did not respond to our request for comment.

The other log reported by Bik was “A glycolytic mechanism regulating an angiogenic switch in prostate cancer,” Posted in Research against cancer in 2007. It was retracted last March. His to remark declared:

This article (1) is being removed at the request of the authors. The images used in the second and third panels of CXCR4 siRNAs in Figure 1B were duplicated from the first and second panels of PC3 control cells in Figure 1B from a previously published article that has since been retracted (2). The authors apologize to the scientific community and deeply regret any inconvenience or challenge resulting from the publication and subsequent retraction of this article.

A copy of this retraction notice was sent to the last known email addresses for 13 of the 13 authors. Ten authors (Jinlu Dai, Younghun Jung, Yu Wang, Aaron M. Havens, Phillip J. Hogg, Evan T. Keller, Kenneth J. Pienta, Jacques E. Nor, Cun-Wu Wang, Russell Taichman) accepted the retraction; three authors (Jianhua Wang, Jincheng Wang and Chuen-Long Wei) did not respond.

The following retraction, from a 2008 article in the Journal of Biological ChemistryThe role of CXCR7/RDC1 as a chemokine receptor for CXCL12/SDF-1 in prostate cancercame in July of this year.

According to the newspaper editorial policies, as editor-in-chief Alex Toker of Beth Israel Deaconess Medical Center told us, the action was called a “takedown” because it was taken by the authors rather than the publisher. (We do not make this distinction in our database.) to remark declared:

This article has been removed by the authors to correct the scientific record, with the exception of Jianhua Wang who could not be contacted. Log analysis and the authors conclude that in Figure 5C, the C4-2BCXCR7 panel was rotated and reused as the C4-2BsiControl panel. Due to the primary data from the C4-2BsiControl panel not supporting the original findings, the authors wish to withdraw this article.

Two other articles have been removed from Research against cancer earlier this month:”CXCR6 induces prostate cancer progression through the AKT/mammalian target rapamycin signaling pathway”, from 2008, and “Characterization of tumor microenvironment-derived stromal cell phosphoglycerate kinase-1 expression in prostate cancer progressionfrom 2010. Both notice identify recycled digits (which, for the last article, PubPeer commenters had noted from May 2020) and declare that Taichman has accepted the withdrawal.

All five articles have Jianhua Wang as first author. Wang, who was affiliated with Michigan for some articles and Shanghai Jiao-Tong University School of Medicine in China for others, did not respond to our request for comment.

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