Presentation of the Zika virus: transmission, origin, pa


Announcement of the publication of a new article for Zoonoses newspaper. Dallas Vue and Qiyi Tang of Howard University College of Medicine, Washington, DC, USA examine the transmission, origin, pathogenesis, animal model, and diagnosis of Zika virus.

The Zika virus (ZIKV) was first discovered in 1947 in Uganda. ZIKV didn’t get much attention until Brazil hosted the 2016 Summer Olympics, and ZIKV reached a global audience. ZIKV is a flavivirus transmitted primarily through mosquito bites, sexual intercourse and, to a lesser extent, breastfeeding. The recent discovery of how ZIKV causes congenital neurodevelopmental defects, including microcephaly, has led to a reassessment of the importance of ZIKV’s interaction with centrosome organization, as centrosomes play an important role in cell division. When ZIKV disrupts the organization of centrosomes and mitotic abnormalities, the differentiation of neural progenitors is impaired, resulting in cell cycle arrest, increased apoptosis and inhibition of differentiation of neural progenitor cells; subsequently, abnormalities in the development of neural cells can lead to microcephaly. To help understand the significance of ZIKV infection, the authors of this article provide an overview of its history, routes of transmission, pathogenesis, animal models, and diagnosis.

Article reference : View of Dallas and Qiyi Tang. Presentation of the Zika virus: transmission, origin, pathogenesis, animal model and diagnosis. Zoonoses. Flight. 1 (1). DOI: 10.15212 / ZOONOSES-2021-0017.

Keywords: Zika virus (ZIKV) centrosome, flavivirus, microcephaly

# # # # # #

Zoonoses is an open access journal for researchers, physicians, veterinarians and public health professionals working in various disciplines of zoonotic diseases.

Zoonoses is now open for submissions; articles can be submitted online at https://mc04.manuscriptcentral.com/zoonoses

Please visit https://zoonoses-journal.org/ to learn more about the journal.

Editorial board: https://zoonoses-journal.org/index.php/editorial-board/

# # # # # #

Zoonoses is available on ScienceOpen (https://www.scienceopen.com/search#collection/839df240-327f-47dd-b636-9b728dff9700).

Submissions can be made using ScholarOne (https://mc04.manuscriptcentral.com/zoonoses).

There are no author submission or article processing fees.

To follow Zoonoses on Twitter @ZoonosesJ; Facebook (https://www.facebook.com/Zoonoses-Journal-100462755574114 ) and LinkedIn (https://www.linkedin.com/company/zoonoses/)

eISSN 2737-7474

ISSN 2737-7466

# # # # # #


Warning: AAAS and EurekAlert! are not responsible for the accuracy of any press releases posted on EurekAlert! by contributing institutions or for the use of any information via the EurekAlert system.



Comments are closed.